Product Lists >> featured >> Coleus forskohlii P.E. (Forskohlin 10%, 20%, 98%)
Forskolin is a naturally occurring diterpene from the Indian plant, Coleus forskohlii, that works as an activator of adenylate cyclase resulting in an increase in the intracellular concentration of cAMP. Laurenza, A., et al. "Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with Trends Pharm. Sci. 10: 442-447 (1989). Barber, R. and Goka, T.J. "Adenylate cyclase activity as a function of forskolin concentration." J. Cyclic Nucleotide Protein Phosphor. Res. 10: 23-29 (1985).
Forskolin acts as a smooth muscle relaxant and vasodilator in a concentration-dependent manner that affects both cytoplasmic calcium levels and contractile element calcium sensitivity. Abe, A. and Karaki, H.J. "Effect of forskolin on cytosolic Ca++ level and contraction in tag heuer replica vascular smooth muscle." J. Pharmacol. Exp. Ther. 249: 895-900 (1989).
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Forskolin acts as a smooth muscle relaxant and vasodilator in a concentration-dependent manner that affects both cytoplasmic calcium levels and contractile element calcium sensitivity. Abe, A. and Karaki, H.J. "Effect of forskolin on cytosolic Ca++ level and contraction in tag heuer replica vascular smooth muscle." J. Pharmacol. Exp. Ther. 249: 895-900 (1989).
It is highly recommended to place order online with escrow service.